To asses if it's the man's fertility that is the cause of childlessness, one or more sperm tests are necessary. Men's sperm quality varies significantly between sperm tests, thus additional examinations can become necessary.
The man needs further examination if one or more of the below conditions apply:
- The sperm tests showed a low sperm count.
- Previous testicular cancer or pre stages to cancer.
- Previous radiation treatment of the scrotum.
- Medical history that suggests infertility such as gynecomastia.
- The above are the most frequent, however, other conditions can be cause for further examination.
A diagnostic analysis of the sperm is necessary. If the sperm count is low a wider analysis may be relevant. In some cases we use MEUSC - also known as Krügers - tests. MEUSC is a morphological sperm analysis that uses a critical assessment of the sperm cells before and after the sperm wash, to determine the percentage of sperm cells that have the perfect shape. This can yield crucial information to determine the treatement type.
This test, performed in the laboratory, determines if the sperm sample is suitable for freezing and thawing. Before freezing we perform a thorough sperm analysis. After freezing individual straws are thawed, to assess the sperm's quality and usability following freezing.
Sperm DNA Integrity test (SDI)
SDI is a test of the sperm cells' chromatin structure. Research suggests that there is a link between poor chromatin packaging and invoulatary childlessness.
The results of an SDI test early in the examination process can give clear suggestions as to whether the treatment should include insimination or IVF. In some cases the chromatin packaging can be so poor that the best solution will be to use a sperm donor.
The sperm sample is to be given to the clinic, but the test is performed at SPZ-lab. Read more about the test on SPZ's website www.spzlab.dk.
One drop of washed sperm containing a small fraction of the complete sperm sample is evaluated by microscope in a Makler-chamber to determine the sperm count.